Commercial airline cabins expose passengers to reduced atmospheric pressure, reduced oxygen availability, reduced humidity, and dry air.1,2,3 These conditions can lead to discomfort with contact lens wear, especially on flights lasting longer than three hours.4,5\r\n\r\nInstillation of lubricating eye drops approved for use with contact lenses may help relieve some eye dryness during your flight.6 Keep in mind that the United States Department of Homeland Security's Transportation Security Administration (TSA) limits the size of any liquid container carried onboard an airplane to a 3.4 ounce (100ml) bottle or less unless the liquids are medically necessary. 3,7 Contact lens solution is considered a medically necessary liquid, so full-size bottles must be declared separately at the entry to the security checkpoint. 7 The solution is then subject to further screening. Solution manufacturers do tend to sell 2 oz. travel size containers of solution for those still wary of TSA restrictions. In the absence of a smaller manufacturer-supplied container of solution, do not attempt to transfer contact lens solution to a smaller container. This allows for contamination of the solution during transfer, which can lead to a serious eye infection.3\r\n